Proposal Assessment c
: Novelty Seeking
proposes to locate a common molecular pathway to which variation
at different loci can all contribute in different sub-populations of
affected individuals. They plan to combine microarray and other gene
expression data with protein annotation and new advances in the understanding
of protein-protein interactions to identify the role of the several
polymorphisms in the developmental pathway leading to NS, using a series of
transgenic rats. The expectation is that the phenomenon can only be understood
at the genetic level by studying how multiple genes interact.
Please assess this proposal, using a scale from 1 to 5.
1. Highest Priority
5. Lowest Priority
6. Skip Item